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From: International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action

1. Drug-specific adverse effects
2. Drug–drug interaction
3. Drug–disease interaction
4. Cognitive impairment/delirium [5,6,7,8]
5. Weight loss, malnutrition [9, 10]
6. Falls [11,12,13,14,15]
7. Hip fractures [12]
8. Urinary incontinence [16]
9. Functional impairment, immobility [17, 18]
10. Hospitalization [17, 19,20,21,22,23,24,25,26]
11. Nursing home, long-term care placement [20,21,22,23,24, 27]
12. Decrease in quality of life [27]
13. Death [27]
14. Reduced treatment adherence [28]
15. Increased cost to the health system and to the individual [17, 20,21,22,23,24, 29,30,31,32,33,34,35,36]